Nano Today Conference

A*STAR Outstanding Publications Award
2009, 2010, 2012, 2013, 2014, 2016 and 2017
A*STAR Patent Power Award
2009, 2010 and 2017
Singapore HEALTH Award
(Platinum) 2012, (Gold) 2008 and 2010
BCA Green Mark Award
2013 (Gold) and 2017 (Gold and Goldplus)

RESEARCH AREAS > Research Staff Details

Nanomedicine/Green Chemistry and Energy


Group Leader

Tel: 6824 7162

View CV

Postdoc Research Associate, Harvard University (USA), 2002-2004
RIKEN Fellow, The Institute of Chemical and Physical Research (Japan), 1996-1997, 2000-2001
Professor, University of Science & Technology of China (China), 1998-2000

Ph.D. in Analytical Chemistry, University of Science and Technology of China, 1992
M.S. in Physical Chemistry, University of Science and Technology of China, 1990
B.S. in Geochemistry, University of Science and Technology of China, 1987

Projects Publications Patents


1. Macromolecular Antimicrobials to Combat Microbes

Chuan Yang, Shrinivas Venkataraman, Xin Ding, Shaoqiong Liu, Jeremy Tan, David Voo, Zhen Chang Liang, Eddy Tan, Shujun Gao, Yuan Yuan, Diane Lim, Hong Wu, Jackie Y. Ying, Yugen Zhang and Yi Yan Yang

The increasing prevalence of antibiotic-resistant infections, such as Methicillin-resistant Staphylococcus aureus (MRSA), has sparked off a pressing need for innovative antimicrobial treatments. IBN has developed a new class of antimicrobial polymers and peptides that can provide a new arsenal against superbugs. Most modern-day antibiotics act on specific molecular targets within the bacteria. While this yields therapeutic specificity, it also allows resistance development through mutation since the bacterial cell structure is generally preserved. The antimicrobial macromolecules are biodegradable and biocompatible, and have broad-spectrum antimicrobial activities against bacteria, yeast and fungi, to destroy multidrug-resistant microbes and prevent drug resistance development.

2. Inorganic Nanomaterials for Antimicrobial Applications

Guangshun Yi, Yuan Yuan, Xiukai Li, Hong Wu, Jackie Y. Ying and Yugen Zhang

IBN has developed inorganic and non-toxic antimicrobial materials specifically for surface disinfection and consumer care applications. Our antimicrobial technologies kill microbes either by physically rupturing their cell membranes or by radical killing mechanism, which prevents the microbes from developing drug resistance and mutating into superbugs. The nanomaterials are low-cost, environmentally friendly and safe. They are effective against a wide range of microbes and would be a powerful weapon against superbugs.

Green Chemistry and Energy

1. Catalytic Systems for Green Synthesis, Carbon Dioxide Utilization and Renewable Energy

Jinquan Wang, Yuan Yuan, Yugen Zhang and Jackie Y. Ying

IBN is investigating the use of green and environmentally friendly technologies for organic synthesis. We are creating highly efficient and selective catalysts such as nano-structured metal oxide catalysts and metal-free polymer catalysts, for the dehydration of biomass into chemicals, fuels and materials. We are also working on converting harmful greenhouse gases into useful chemicals or fuels, for example, the conversion of carbon dioxide to carbonates with organocatalysts. In addition, we are working on the production of hydrogen from water using photocatalysis and photo-electrochemical approaches.

2. Nanomaterials for Battery and Energy Applications

Jinhua Yang, Yue Yu, Xun Yuan, Ayman Amin Abdelhamid Amin, Jian Liang Cheong, Jinquan Wang, Siti Nurhanna Riduan, Alex Eng, Su Seong Lee, Yugen Zhang and Jackie Y. Ying

Nanomaterials have attracted significant attention for energy applications in recent years due to their excellent properties. Our research is focused on the design and synthesis of a variety of nanostructures, including nanoclusters with customized sizes, nanosheets, nanocrystals with tailored morphologies, and mesostructured materials, nanocomposite systems, porous organic polymers and metal organic frameworks. These novel materials are promising for use in stable, efficient, high-capacity battery and supercapacitor applications.


Generation of ‘‘Off-the-Shelf’’ Natural Killer Cells from Peripheral Blood Cell-Derived Induced Pluripotent Stem Cells
Stem Cell Reports, (2017)
(IF: 7.338) article

Aptamer-Based ELISA Assay for Highly Specific and Sensitive Detection of Zika NS1 Protein
Analytical Chemistry, (2017)
DOI: 10.1021/acs.analchem.7b02862.
(IF: 6.320) article

Genetic Alphabet Expansion Transcription Generating Functional RNA Molecules Containing a Five-Letter Alphabet Including Modified Unnatural and Natural Base Nucleotides by Thermostable T7 RNA Polymerase Variants
Chemcial Communications, (2017)
DOI: 10.1039/c7cc06661a.
(IF: 6.319) article



Research Positions

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