A*STAR Outstanding Publications Award
2009, 2010, 2012, 2013, 2014 and 2016
A*STAR Patent Power Award
2009 and 2010
Singapore HEALTH Award
(Platinum) 2012, (Gold) 2008 and 2010

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INNOVATIONS FOR TOMORROW

Announcements

IBN Wins A*STAR Outstanding Publications Award for the Sixth Time


IBN won the 2016 A*STAR Outstanding Publications Award

April 18, 2016 – IBN has won the 2016 A*STAR Outstanding Publications Award again! The award recognizes the A*STAR biomedical research institute with the most quality publications per research staff in high impact journals last year. This is the sixth time that IBN has won the award since 2009. IBN Group Leader Professor Hanry Yu also received the A*STAR Scientist-Entrepreneur Award 2016 for co-founding InvitroCue Pte Ltd, a spin-off company from IBN.

“We are delighted to clinch the A*STAR Outstanding Publications Award again this year, and for the sixth time. This award is dedicated to all our staff and students for their excellent research work. We are also pleased that Hanry has received the A*STAR Scientist-Entrepreneur Award for our spin-off company InvitroCue, and more importantly that our technologies are making a commercial impact,” said IBN Executive Director Professor Jackie Y. Ying.

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International Honors for IBN’s Scientific Advisory Board Members

April 14, 2016 – Two of IBN’s Scientific Advisory Board Members received international recognition for their scientific contributions recently.

Professor Galen D. Stucky, Co-Chair of the IBN Scientific Advisory Board, and Professor of Chemistry and Biochemistry, and of Materials at the University of California, Santa Barbara, has been selected as a Fellow of the U.S National Academy of Inventors for 2015. He was recognized for his highly prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development, and the welfare of society.

Professor Allan S. Hoffman, IBN Scientific Advisory Board Member, has been included in Thomson Reuters’ list of the “World’s Most Influential Scientific Minds” for 2015. He is currently Emeritus Professor of Bioengineering at the University of Washington. The report, which was released in January 2016, is a citation analysis identifying the scientists who have made the most significant global impact within their respective fields of study, as determined by their fellow researchers.

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Patterning Pluripotency
Insights into how external mechanical forces affect stem cell behavior could advance regenerative medicine efforts


Stem cell colonies of differing shapes: (top row) phase images, (bottom row) intensity of T cell expression after 1 day induction.
Reprinted from Ref. 1, Copyright (2015), with permission from Elsevier

March 9, 2016 – Stem cells are an effective tool for repairing or replacing damaged or diseased tissues, but only if they can be reliably developed from their flexible ‘pluripotent’ state into a mature ‘differentiated’ state. Researchers from the A*STAR Institute of Bioengineering and Nanotechnology have learned how to control the state of stem cells by altering the physical environment in which they are cultured.

Chemical signals and mechanical forces help determine which cells differentiate and which remain pluripotent. Researchers have gained several insights into the chemical ‘cues’, but are still struggling to understand how to manipulate the structure of stem cell colonies in order to control their behavior. “There has been a lot of trial and error because of the lack of engineering principles to guide the control of cellular responses,” says Prof Hanry Yu. His team focused on E-cadherin and integrin, two cellular adhesion proteins that are believed to be involved in regulating stem cell development. Intriguingly, both proteins act via a common signaling factor, Rho-ROCK-myosin II, raising questions about how they induce distinct cellular fates.

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IBN in the News

Progress Towards a Broad Antiviral Treatment
The Economist , 30 Apr 2016

Lab Profile: Jackie Y. Ying
Materials Today , 20 Apr 2016

Toward a Resistance-Proof Antiviral that Can Treat Many Diseases
PhysOrg, 20 Apr 2016

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FEATURED PUBLICATIONS

NEW! Copper Catalysed Alkynylation of Tertiary Amines with CaC2 via sp3 C-H Activation
Green Chemistry, (2016)
DOI: 10.1039/C6GC00872K.
(IF: 8.020) article

Differential Expression Between Human Dermal Papilla Cells from Balding and Nonbalding Scalps Reveals New Candidate Genes for Androgenetic Alopecia
Journal of Investigative Dermatology, (2016)
DOI: 10.1016/j.jid.2016.03.032.
(IF: 7.216) article

Selective Aerobic Oxidation of Furfural to Maleic Anhydride with Heterogeneous Mo-V-O Catalysts
Green Chemistry, (2016)
DOI: 10.1039/C6GC00508J.
(IF: 8.020) article

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