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Intelligent Sensor Informs You to Change a Diaper via SMS

Image 1: The IBN researchers who developed the diaper wetness monitoring system.
From left: Dr Min Hu, Prof Jackie Y. Ying, Dr Rensheng Deng and Dr Guolin Xu.

August 12, 2015 – Diapers could soon come with a sensor that alerts caregivers by SMS when the diapers are soiled. Researchers from the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR have invented an “intelligent continence management system” comprising a thin disposable sensor strip, a compact wireless transmitter, a receiver and software, which has the potential to improve the care of elderly and bedridden patients.

“Lying in soiled diapers for prolonged periods is not only uncomfortable and unhygienic, but may also cause skin rashes and infection for the wearer. While increasing the frequency of diaper checks and changes may help to reduce this problem, it would also add to the workload of caregivers. Clearly, there is a need for an alternative solution,” said IBN Executive Director, Professor Jackie Y. Ying, who led the research effort.

Timely replacement of soiled diapers is a challenge for caregivers of patients who are unable to communicate this need, such as those who suffer from aphasia, the loss of speech after a stroke or brain injury.

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Tallying White Blood Cells on Paper
A cost effective means for counting white blood cells promises to improve diagnosis in low-resource areas

White blood cells (gray spheres with spikes) are too large to pass through the pores in paper and thus become trapped on the surface. The gold nanoparticles (red spheres) that bind to the cell surface result in the formation of a dark spot (see inset). In the absence of white blood cells, all gold nanoparticles would flow through the paper.
Reprinted from Ref. 1, Copyright 2015, with permission from Elsevier.

July 15, 2015 – An inexpensive, low-tech method for counting white blood cells, that uses gold nanoparticles and paper has been devised by researchers from the A*STAR Institute of Bioengineering and Nanotechnology. The simple, low-cost and compact nature of this method makes it particularly attractive for point-of-care applications in settings that lack sophisticated medical resources.

White blood cell count is a vital indicator of a person’s health. Too many white blood cells may indicate a bacterial infection, tissue damage or inflammatory diseases such as arthritis or allergies, whereas too few could denote a viral infection or bone marrow deficiency. Furthermore, white blood cell count can be used to predict a person’s risk of developing conditions such as diabetes and heart disease.

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YRP Student Wins Fourth Place at the Intel International Science and Engineering Fair

Congratulations to our Youth Research Program (YRP) student Claudia Lee on winning the 4th Award at the 2015 Intel International Science and Engineering Fair on May 10-15 in Pittsburgh, Pennsylvania. 18-year-old Claudia from Raffles Institution clinched the fourth place in the Chemistry category for her IBN research attachment project on utilizing metal-free click chemistry for the development of peptide-based biomaterials, out of 104 chemistry projects from around the world.

More than 1,700 of the most promising young scientists, engineers and mathematicians participated in the world’s largest international pre-university science competition. Claudia was one of 6 representatives from Singapore, and had won the Gold Award at the 2015 Singapore Science and Engineering Fair in March.

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IBN in the News

Intelligent Sensor Informs You to Change a Diaper via SMS
Asia Pacific Biotech News Magazine, 01 Sep 2015

Smart Sensor Informs Caregivers to Change Diapers
HospiMedica, 27 Aug 2015

A Text Message to Indicate the Need for Diaper Change!
Biotechin.Asia, 24 Aug 2015

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NEW! Codelivery of Dual Drugs from Polymeric Micelles for Simultaneous Targeting of Both Cancer Cells and Cancer Stem Cells
Nanomedicine, 10 (2015) 2819-2832.
(IF: 5.413) article

A Computational Method for Studying the Relation Between Alternative Splicing and DNA Methylation
Nucleic Acids Research, (2015)
DOI: 10.1093/nar/gkv906.
(IF: 9.112) article

Intramolecularly H-Bonded Aromatic Pentamers as Modularly Tunable Macrocyclic Receptors for Selective Recognition of Metal Ions
Journal of the American Chemical Society, (2015)
DOI: 10.1021/jacs.5b07123.
(IF: 12.113) article



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