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INNOVATIONS FOR TOMORROW

Announcements

Second IBN International Symposium on Nanomedicine and Nanoassays in Singapore

IBN organized the 2nd IBN International Symposium (IBN-is) on December 8-9, 2014 at the Matrix, Biopolis. This year’s theme on Nanomedicine and Nanoassays’ represents two exciting areas that are set to transform healthcare and diagnostics.

The symposium featured 17 invited speakers from renowned institutions worldwide, 17 contributed oral and 56 poster presentations. 350 local and international delegates attended the two-day symposium.

A Special Forum for Students was held in the afternoon of December 9, where a distinguished panel shared personal insights from their careers in industry, academia and hospital, to inspire and encourage students to pursue careers in research.

To find out more, please visit: www.ibn-is.com.

Flat, Diamond-Shaped Plates of Lithium Iron Phosphate Improve Discharge Voltages


Cathodes made from hollow plates of lithium iron phosphate improve the performance of lithium-ion batteries.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

November 19, 2014 – Hollow, crystalline particles of lithium iron phosphate can enhance the performance of lithium-ion batteries by enabling an easier flow of lithium ions, A*STAR researchers have found.

Lithium-ion batteries are ubiquitous in cell phones, laptops and other portable electronic devices, and are increasingly used in electric cars. During charging, lithium ions inside the battery leave the positive cathode, travel through a liquid electrolyte and enter the negative anode (often made of carbon). This flow of ions reverses during discharging.

But conventional cathode materials have serious drawbacks: lithium cobalt oxide, for example, is toxic and expensive, and while lithium iron phosphate is cheaper and nontoxic, it suffers from low electrical conductivity.

Prof Jackie Ying of the A*STAR Institute of Bioengineering and Nanotechnology in Singapore and colleagues have now developed a form of lithium iron phosphate particles that act as a cathode for better performance. The diamond-shaped particles, which look like miniature melon seeds, are hollow, and have a crystalline structure that is easier for lithium ions to enter (see image).

Read more.

IBN Develops Green Tea-Based ‘Missiles’ to Kill Cancer Cells More Effectively


The IBN research team (from right to left): Dr Susi Tan, Dr Motoichi Kurisawa, Prof Jackie Y. Ying, Dr Shujun Gao,
Dr Joo Eun Chung and Ms Nunnarpas Yongvongsoontorn.

October 6, 2014 – Green tea has long been known for its anti-oxidant, anti-cancer, anti-aging and anti-microbial properties. A group of researchers from the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR has taken the health benefits of green tea to the next level by using one of its ingredients to develop a drug delivery system, which kills cancer cells more efficiently.

A key ingredient in green tea, epigallocatechin gallate (EGCG), is an antioxidant which is known to have therapeutic applications in the treatment of many disorders including cancer.

Using EGCG, IBN researchers have successfully engineered nanocarriers that can deliver drugs and kill cancer cells more efficiently. Their work was published recently in the leading journal Nature Nanotechnology

Read more.

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IBN in the News

Local Scientists Collaborate with Clinicians to Develop Targeted Therapies
Lianhe Zaobao, 09 Dec 2014

A Hollow Promise for Better Batteries
A*STAR Research , 19 Nov 2014

Nano Missile Fights Cancer with Green Tea
AsiaOne, 21 Oct 2014

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FEATURED PUBLICATIONS

Antimicrobial Hydrogels: A New Weapon in the Arsenal Against Multidrug-Resistant Infections
Advanced Drug Delivery Reviews, 78 (2014) 46-62.
(IF: 12.707) article

Role of Grafted Alkoxybenzylidene Ligand in Silica-Supported Hoveyda–Grubbs-Type Catalysts
Chemical Communications, (2014)
DOI: 10.1039/c4cc08627a.
(IF: 6.718) article

Benzyl Chloride-Functionalized Polycarbonates: A Versatile Platform for the Synthesis of Functional Biodegradable Polycarbonates
Macromolecules, (2014)
DOI: 10.1021/ma501734y.
(IF: 5.927) article

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