A*STAR Outstanding Publications Award 2009, 2010, 2012 and 2013
A*STAR Patent Power Award 2009 and 2010
Singapore HEALTH Award (Platinum) 2012, (Gold) 2008 and 2010
Recycled Plastic Proves Effective in Killing Drug-Resistant Fungi
IBN and IBM discover new medical application for converted PET bottles
The IBN researchers who were part of the breakthrough published in Nature Communications (from left to right): Dr Hong Wu, Dr Shaoqiong Liu, Prof Jackie Y. Ying, Dr Yi Yan Yang and Dr Shrinivas Venkataraman.
Singapore, December 9, 2013 – Researchers at Singapore’s Institute of Bioengineering and Nanotechnology (IBN) and California’s IBM Research – Almaden (IBM) have discovered a new, potentially life-saving application for polyethylene terephthalate (PET), which is widely used to make plastic bottles. They have successfully converted PET into a non-toxic biocompatible material with superior fungal killing properties. As reported in Nature Communications1, their new material proved particularly effective in destroying drug-resistant fungi and fungal biofilm, displaying great potential as an antifungal agent to prevent and treat topical fungus-induced diseases such as skin infections and keratitis.
IBN Executive Director Professor Jackie Y. Ying shared that, “A key focus of IBN’s nanomedicine research efforts is the development of novel polymers and materials for more effective treatment and prevention of various diseases. Our latest breakthrough with IBM allows us to specifically target and eradicate drug-resistant and drug-sensitive fungi strains and fungal biofilms, without harming surrounding healthy cells. We hope to eventually apply this technology clinically to help the large number of patients worldwide who suffer from fungal infections.”
Nanotechnology Experts to Gather in Singapore for 3rd Nano Today Conference
December 3, 2013 – Over 400 scientists worldwide will converge in Singapore for the 3rd Nano Today Conference which will be held at the Biopolis on December 9 to 11, 2013. Organized by Nano Today, a leading journal for nanoscience and nanotechnology, the Institute of Bioengineering and Nanotechnology (IBN) and Elsevier, the three-day conference will showcase the latest research advances in nanostructured materials and systems for diverse applications in areas such as biomedical, electronic, chemical and energy.
Chaired by Nano Today Editor-in-Chief and IBN Executive Director, Professor Jackie Y. Ying, this conference will feature 3 plenary lectures by Professor Younan Xia (Georgia Institute of Technology, USA), Professor Joseph M. DeSimone (University of North Carolina, USA) and Professor Mostafa A.
El-Sayed (Georgia Institute of Technology, USA), invited talks by 25 distinguished scientists from internationally renowned institutions, as well as 17 contributed oral and over 220 poster presentations.
“Nanotechnology offers a new approach to tackling many problems, and the numerous research breakthroughs in recent years have demonstrated the potential of this rapidly evolving field. The Nano Today conference series aim to feature the latest advances and applications of nanotechnology. IBN is delighted to host the third conference in Singapore with Nano Today and Elsevier. We are honored to have a large number of leading experts as invited speakers for our conference, and the participation of researchers and students from 45 countries. We look forward to a stimulating and exciting meeting,” said Professor Jackie Y. Ying.
New Hydrogel from IBN and IBM Improves Delivery of Anti-Cancer Drug
Research breakthrough promises more efficient breast cancer treatment
The IBN research team comprising Dr Yi Yan Yang, Dr Victor Ng, Dr Shujun Gao and Dr Ashlynn Lee (anti-clockwise from bottom right)
October 31, 2013 – The Institute of Bioengineering and Nanotechnology (IBN) and IBM Research (IBM) have developed a new non-toxic hydrogel that is capable of shrinking breast cancer tumors more rapidly than existing therapies. As described in their publication in Advanced Functional Materials, the Vitamin E-incorporated hydrogel can be easily injected under the skin without causing any inflammatory response, and releases anti-cancer drugs in a sustained manner over several weeks. This reduces the need for frequent drug administration, paving the way for the tumors to be eradicated in fewer treatments.
According to IBN Executive Director Professor Jackie Y. Ying, “Since 2003, IBN has adopted a multi-pronged approach toward cancer research. Our multidisciplinary research teams are working with various industrial, clinical and academic partners to develop new materials and tools to improve cancer diagnosis and treatment. This latest breakthrough with our long-term partner, IBM Research promises more efficient administration of anti-cancer drugs and more effective treatment of breast cancer, which we hope would benefit breast cancer patients worldwide.”
IBN in the News
Improving Drug Delivery for Breast Cancer Treatment
A*STAR Research, 04 Dec 2013
Nanotechnology Experts to Gather in Singapore for 3rd Nano Today conference
Nanotechnology Now , 03 Dec 2013
New Hydrogel Helps Reduce Breast Cancer Tumor Size in Fewer Treatments than Traditional Therapies
Financial News, 05 Nov 2013
Co-Delivery of Thioridazine and Doxorubicin Using Polymeric Micelles for Targeting Both Cancer Cells and Cancer Stem Cells
Biomaterials, 35 (2014) 1096-1108.
(IF: 7.604) article
Injectable Hydrogels from Triblock Copolymers of Vitamin E-Functionalized Polycarbonate and Poly(ethylene glycol) for Subcutaneous Delivery of Antibodies for Cancer Therapy
Advanced Functional Materials, (2013)
(IF: 9.765) article
Fine Control Over the Size of Surfactant−Polyelectrolyte Nanoparticles by Hydrodynamic Flow Focusing
Analytical Chemistry, 85 (2013) 5850-5856.
(IF: 5.695) article
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