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INNOVATIONS FOR TOMORROW

Announcements

A Molecular ‘Straw’
Powered by a proton gradient, a world-first helical molecule transports water across membranes


The blue and orange molecules are identical, and stack on each other to form the helix. The central tube of the helix holds a one-dimensional string of water molecules.

April 1, 2015 – Getting water across lipid membranes is not easy. In nature, molecules called aquaporins, discovered in the 1990s, move water from one side of a biological membrane to another, but the molecules are fragile and bulky. Now, researchers from the A*STAR Institute of Bioengineering and Nanotechnology have synthesized a much smaller molecule, which behaves like a ‘molecular drinking straw’ and which may have applications in water purification and elsewhere.

For some years, Dr Huaqiang Zeng led a team aiming to produce tubular molecules that could pipe water across membranes. In 2012, they created molecules that stacked into a helical tube; unfortunately, this tube was not particularly good at holding water in its central tunnel.

Undeterred, Zeng’s team set out to modify that molecule. Substituting a carboxyphenyl group for a carboxybenzyl group was just what was needed – once again the molecules stacked into a helix, but this time it comfortably held a ‘string’ of water molecules.

Read more.

Two Gold and One Bronze for IBN’s Youth Research Program Students at the Singapore Science and Engineering Fair


IBN’s Youth Research Program Students win Two Gold and One Bronze at the Singapore Science and Engineering Fair 2015. From left: Tommy Ong, Claudia Lee and Judy Hong.

Congratulations to our Youth Research Program students and their IBN mentors for winning two Gold Awards and one Bronze Award at this year’s Singapore Science and Engineering Fair held on March 11-12, 2015.

The annual competition is organized by the Ministry of Education, A*STAR and Science Centre Singapore for all secondary and pre-university students to showcase their research projects in the past year.

The most outstanding winners will go on to participate in the Intel International Science and Engineering Fair, the largest international pre-university science competition in the world. We are delighted that both our gold winners have been selected as two of only six projects from over 100 winning entries to represent Singapore in this year’s event which will be held in Pittsburgh, Pennsylvania in May to compete with young researchers from over 70 countries.

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Singapore’s Institute of Bioengineering and Nanotechnology Wins Brunei Crown Prince Innovation Award


The IBN research team (from left) Dr Joo Eun Chung, Prof Jackie Y. Ying and Dr Motoichi Kurisawa won the Brunei Crown Prince Innovation Award with their green tea drug delivery system invention.

March 18, 2015 – A new drug delivery system from the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR that uses green tea to fight cancer has won the Grand Prize at The Crown Prince Creative, Innovative Product and Technological Advancement (CIPTA) Award 2015. The award ceremony was held in Brunei on Saturday, March 14, 2015.

The CIPTA Award is a biennial competition organized by the Institut Teknologi Brunei and Brunei LNG to encourage and develop innovations in Brunei. The submissions were judged by an international panel of experts in academia and industry led by Professor Salim Al-Hassani, President of the Foundation for Science, Technology and Civilisation, UK and Professor of Mechanical Engineering, University of Manchester.

Read more.

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IBN in the News

Green Tea Based Anti-Cancer Therapy
Biotech in Asia, 17 Apr 2015

Treating Tumors with Tea
A*STAR Research , 15 Apr 2015

Nanotechnology Research Finds A Way to Treat Tumors with Green Tea
Nanowerk, 15 Apr 2015

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EVENTS

2015
5 May
IBN Seminar Series: Creation of a Genetic Alphabet Expansion System Using Unnatural Base Pairs and its Applications Toward Diagnostics and Therapeutics by Prof. Ichiro Hirao, RIKEN Center for Life Science Technologies, Japan

12 May
IBN Seminar Series: Differential Sensing Concepts and Applications by Prof. Eric Anslyn, Department of Chemistry, The University of Texas at Austin, USA

6 Dec - 10 Dec
4th Nano Today Conference

Event Calendar   

FEATURED PUBLICATIONS

Synthesis of Phase-Pure Li2MnSiO4@C Porous Nanoboxes for High-Capacity Li-Ion Battery Cathodes
Nano Energy, 12 (2015) 305-313.
(IF: 10.211) article

Synthetic β-Sheet Forming Peptide Amphiphiles for Treatment of Fungal Keratitis
Biomaterials, 43 (2014) 44-49.
(IF: 8.312) article

Porous MnO/Mn3O4 Nanocomposites for Electrochemical Energy Storage
Nano Energy, (2015)
DOI: 10.1016/j.nanoen.2015.03.026.
(IF: 10.211) article

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